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Stimulating Axon Regrowth After Spinal Cord Injury - Neuroscience News 01/23/2023

Following spinal cord injury, a course of daily noninvasive suprathreshold high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) activates the BRAF canonical downstream effectors MAP2K1/2 and modulates the expression of a set of regeneration-related transcription factors and enables functional CST axon regrowth and sprouting.

Stimulating Axon Regrowth After Spinal Cord Injury - Neuroscience News High-frequency repetitive transcranial magnetic stimulation (rTMS) activates MAP2K signaling and enhanced axon regeneration and functional recovery following spinal cord injury.

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New research is attempting to better understand (beyond neuronal energy metabolism) how mitochondrial dysfunction contributes to neurological disorders and diseases and has yielded emerging information about the mitochondrial basis of neural health in neurodegeneration, organelle dynamics, cell death, immunometabolism, etc. Distinct mechanisms and pathways that protect mitochondrial health also intersect to produce neurological health support, metabolic plasticity, and stress responses in the nervous system (as well as to contribute to the pathology of neurological disorders and diseases) and are integrated within these mitochondrial signaling pathways.

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