Shepherd Lab
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In particular we are interested in the elucidation of the protein machinery at the synapse that governs long-term storage of information, and how basic cell biological processes have been elaborated in neurons for the purpose of modulating synaptic transmission. In addition, we are interested in how these processes go awry in neurological diseases. The overall goal of our research program is to in
08/08/2017
It's been a great summer for the lab, with two papers published! Here's the first: lead (and sole!) author - Elissa Pastuzyn
Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome Angelman syndrome (AS) is a neurodevelopmental disorder that results from deletions or mutations in chromosome 15, which usually includes the UBE3A gene. Ube3A protein is an E3 ubiquitin ligase that ubiquitinates proteins and targets them for degradation. The immediate-early gene Arc, a master regul...
Congrats to Andrew Taibi for passing his thesis proposal defense and becoming the second Shepherd Lab graduate student to qualify to Ph.D. candidacy!
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36S Wasatch Drive, 4340 Sorenson Molecular Biotechnology Building
Salt Lake City, UT
84132
