ZenBud
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04/03/2026
79% Anxiety Remission in Just 4 Weeks Using Ultrasound on the Vagus Nerve (Pilot Study)
We just published our latest study in JMIR Neurotechnology, and the results are exciting:
Using low-intensity focused ultrasound (LIFU) to stimulate the auricular branch of the vagus nerve, we achieved a 79% anxiety remission rate in just 4 weeks using a simple wearable device called ZenBud.
Here’s what you need to know 👇
🔗 Full Study:
🧾 https://doi.org/10.2196/69770
🧪 How the Study Worked:
✅ 28 people with moderate to severe anxiety
✅ Used ZenBud LIFU headset at home
✅ 5 minutes a day, for 4 weeks
✅ No restrictions on time or activity
✅ Measured: anxiety, depression, PTSD, sleep
📊 Results:
• Anxiety: 79% remission
• Depression: clinically meaningful reduction in 71%
• PTSD: similar gains
• Sleep: significantly improved
👉 All with strong statistical backing
🛡️ Safety & Usability:
• Only 1 mild side effect (brief jitteriness)
• 89% said the headset was easy to use
• 79% felt their quality of life improved
👏 Easy, safe, and impactful
🧬 How It Works:
The vagus nerve plays a big role in calming the nervous system.
LIFU may boost "vagal tone" to help quiet anxiety.
We also saw heart rate variability (HRV) jump 10–27 points.
Next step: more studies with imaging (like fMRI) and biomarkers.
⚠️ Important Limitations:
🔸 Small group (28 people)
🔸 No placebo/control group
🔸 Study lasted just 4 weeks
We’re working toward larger trials and longer-term data.
🔬 Help Us Go Further:
We’re looking for:
👩🔬 Researchers
🧠 Neuroscientists
🧪 Clinicians
💻 Engineers
🌍 Citizen scientists
💰 Funders & partners
...to take this work to the next level.
🤝 Let’s Collaborate:
Are you interested in non-invasive mental health tech?
Want to help expand this research or develop new tools?
Reach out: [email protected]
💬 Join the Conversation:
What do you think of our findings?
Have you tried vagus nerve stimulation or other wearable tech for anxiety?
Drop your thoughts in the comments or DM us, we’re building a community of curious minds.
03/31/2026
If you’re always on edge, it’s not just in your head.
Your nervous system might be stuck in overdrive.
It’s time to reset, naturally.
03/30/2026
The vagus nerve helps slow your heart rate, deepen breathing, improve digestion, and bring your body back to calm-naturally.
ZenBud is designed to support this process, helping you activate your body’s natural calming system through non-invasive stimulation.
Chronic stress isn’t just a mental burden — it’s a full-body emergency your system can’t outrun.
When the sympathetic nervous system is stuck in “on” mode, your body pumps out cortisol nonstop. And while cortisol is essential in short bursts, elevated levels over time can fuel inflammation, disrupt immune function, and drain energy in ways most people never realize.
In this conversation, our expert breaks down one of the most misunderstood players in the health world: the vagus nerve.
Contrary to the hype, the vagus nerve isn’t a magical cure-all — its real job is even more important:
• Keeps you alive by helping regulate cortisol
• Supports immune resilience
• Maintains communication between the brain and gut
• Stabilizes the limbic system
• Enables recovery, rest, and long-term health
👉 Watch the full clip to learn why chronic stress affects so much more than your mood — and what your vagus nerve is really doing to keep you healthy.
10/14/2025
Tired, wired, and running on empty?
Your nervous system might be calling for backup.
ZenBud™ uses low-intensity focused ultrasound to stimulate your vagus nerve and help your body shift from “fight or flight” to “rest and restore.”
No drugs. No guesswork. Just calm-on demand.
Backed by clinical results
✅78% of users reached remission in just 4 weeks
✅Easy, wearable, and non-invasive
✅Ready to listen to what your body’s been trying to say?
Tap the link in bio to learn more and take control of your calm.
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