Pannier Lab

issue engineering, and protein-cell-biomaterial interactions. Within the nonviral gene delivery theme, our aim is to determine and understand the mechanisms that render cells responsive to the transfer of genetic material (e.g. DNA), concentrating on the cell microenvironment, the interaction between cells and biomaterials, and the intracellular processes and subsequent signaling involved during nonviral gene delivery. Within the tissue engineering theme, our objective is to develop biomaterial scaffolds and culture systems to understand and promote tissue, organ, and organism development, regeneration, and growth. Within the protein-cell-material interaction theme, projects aim to make use of a novel combinatorial spectroscopic ellipsometry and quartz crystal microbalance with dissipation analytical technique to uncover new and unique information on processes that occur at biomaterial interfaces, which are critical to the performance of biomaterials in biotechnological and therapeutic applications. The experimental approaches developed in the Pannier Lab provide valuable insights to the fields of gene delivery and biomaterials, with very promising potential for future scientific discovery and translation to therapeutic, biotechnological, and tissue engineering applications.