The Osteosarcoma Institute
Osteosarcoma is the most common bone cancer, affecting about 900 people each year in the U.S., most of whom are children, adolecents, and young adults. Survival rates have remained largely unchanged for decades, leaving too many patients without effective options after first-line treatment. The Osteosarcoma Institute (OSI), founded in 2017, is exclusively dedicated to changing that reality. Guided
07/09/2026
An active 21-year-old, Emily’s osteosarcoma diagnosis came out of left field. But with perseverance, a positive mindset, and plenty of rest, she was able to fight and is now in remission.
“These days, I am trying to get back to doing the things I did before, such as hiking and walking and just enjoying my life,” Emily says. “I have some trying days, of course, but I focus on the positive, which is the basis of the advice I share with those who has been diagnosed with osteosarcoma.”
Read Emily’s story and advice: osinst.org/blog/emilys-journey-through-osteosarcoma-cancer-diagnosis-treatment
This , and every month, we are focused on a cure for osteosarcoma. A generous grant covers OSI’s administrative expenses, so 100% of all donations made to OSI go directly toward osteosarcoma research.
Donate today: osinst.org/sarcoma-awareness-month
06/25/2026
Rosandra N. Kaplan, MD, is on a mission to prevent tumor metastasis, the leading cause of cancer-related deaths.
A pediatric oncologist from the National Cancer Institute, Dr. Kaplan’s approach is to take an element of a tumor’s microenvironment that enables tumor growth and reprogram it to attack metastatic cancer. Her experimental cancer therapy involves myeloid cells, which are found in the immune system and respond to infection or injury. Myeloid cells interpret osteosarcoma as an injury that needs to be healed, so they send messages to T-cells to quiet down which inadvertently fuels the cancer growth.
“Since myeloid cells play a role in cancer growth, it might seem tempting to try to eliminate them altogether, but these cells are crucial to the body’s functioning,” Dr. Kaplan says. “We can’t beat them, so we have to join them.”
Learn more about Dr. Kaplan’s research to prevent tumor metastasis: osinst.org/blog/kaplan-research
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