JAMA Psychiatry

Targeted psychological and psychosocial interventions for , including avatar therapy, reduced the severity of with small to medium effects and high acceptability.

https://ja.ma/4et5RKP

Among patients with , antipsychotic nonresponse was associated with elevated medial frontal glutamate, choline, and myo-inositol, supporting further investigation of glutamatergic and inflammatory pathway interventions.

Neurometabolites and Antipsychotic Response in Psychosis This mega-analysis assesses differences in neurometabolites in antipsychotic nonresponsive compared to antipsychotic-responsive psychosis using individual participant data and meta-analysis.