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Functional dissection of neural circuitry using a genetic reporter for fMRI - Nature Neuroscience 03/29/2022

Ghosh et al. recently used , SHIELD, fMRI & a novel genetic probe to explore the functional roles of neural populations in interconnected regions of the rat brain. Check out their paper in Nature !

Functional dissection of neural circuitry using a genetic reporter for fMRI - Nature Neuroscience This study introduces genetically encoded imaging probes that convert intracellular calcium signaling into hemodynamic fMRI responses. The authors show how the probes can be used to map information flow in reward-related brain circuitry in rats.

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