Lysosome Febs Advanced Course

Dr. Volkan Seyrantepe is going to give a remarkable lecture: “Disturbed catabolic pathways in animal models of L*Ds” in FEBS Advanced Lecture Course: 360° Lysosome on October 9, 2021 at 14.30 pm!

Prof Seyrantepe’s research includes biological role of sialidases in complex cellular events such as glycolipid degradation and lysosomal storage diseases. As PI, Faculty, Senior Scientist and co-Investigator on national and international-funded grants (TUBITAK, EMBO, Marie Curie, German BMBF), Prof Seyrantepe has the expertise, leadership, training, and strong motivation necessary to carry out research projects in the field of lysosomal storage diseases. Dr. Seyrantepe successfully administered the projects collaborated with other researchers from USA, Canada, Japan, Germany, Denmark, Colombia and France, and produced several peer-reviewed publications. His current research mainly focuses on the better understanding of pathophysiology of lysosomal storage disease, Tay-Sachs using recently generated and validated mouse model. Dr Seyrantepe’s lab is also funded by TUBITAK through 3 COST ACTIONS: CA17103 DARTER (Delivery of Antisense RNA Therapies), CA18103 INOGLY (Innovation with Glycans: New Frontiers from Synthesis to New Biological Targets and CA19105 EpiLipidnet (Pan-European Network in Lipidomics and Epilipidomics) and Bosphorus Bilateral agreement fund between Turkey and France to further understand the etiopathogenesis of Tay-Sachs disease. Currently, his team uses siRNA based therapeutic approach to cure Tay-Sachs mouse model. He also investigates the combined effects of small drug molecules (rapamycine and lithium) on induction of autophagy in neurons, neuroglia and skin fibroblasts from Tay-Sachs Hexa-/-Neu3-/- mice as well as Tay-Sachs patients and address the role of N-glycans in the regulation of autophagy. His ongoing research may have potential to contribute for the development of new therapeutic strategies to cure devasting Tay-Sachs disease.

Honor: 2007 Foundation for research into Children’s diseases, Canada- Fondation de la recherche sur les maladies infantile”- Prix d’excellence 2007: Prix chercheur post-doctoral 2007 Best Post-Doctoral Researcher in Canada presented by Pfizer.

*Ds