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MODEL SELECTION AND MAXIMUM LIKELIHOOD IN MEGA| LECTURE 4

MEGA Interface Explained in Detail | Complete Guide to Title Bar, Toolbar, Modules & Panels | Lecture 2

What is MEGA Software? Full Introduction to Molecular Evolutionary Genetics Analysis for Beginners
In this video, I provide a complete introduction to MEGA (Molecular Evolutionary Genetics Analysis) software, one of the most widely used tools in molecular biology and phylogenetics. You will learn what MEGA stands for, who developed it, when it was first released, and why it has become essential for researchers and students working with DNA, RNA, and protein sequence data.
I also explain the major functions of MEGA, including multiple sequence alignment (ClustalW and MUSCLE), genetic distance calculation (Kimura 2-Parameter and other models), phylogenetic tree construction (Neighbor-Joining, Maximum Likelihood, UPGMA), bootstrap analysis, model selection, and evolutionary analysis such as dN/dS estimation.
This video is handy for BS, MSc, MPhil, and PhD students working on DNA barcoding, molecular evolution, and phylogenetic analysis. In the next video, we will cover installation and a practical walkthrough of the MEGA interface.
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