Shoaib Kanwal Academy

Causes of chronic constipation

Treatment of VTE (DVT/PE)
1.Loading dose of apixaban 10mg BD x7 days followed by 5mg BD thereafter or
2.Loading dose of Rivaroxaban 15mg BD x21 days followed by 20mg OD thereafter

Stroke prevention in Afib
1.Apixaban 5mg BD or
2.Rivaroxaban 20mg OD (15mg OD if CrCl is 15-50ml/min)
No loading dose is required in afib

However the dose of apixaban is reduced in afib to 2.5 mg BD in patients who meet at least two of the following three criteria:
1.age ≥80 years
2.body weight ≤60 kg
3.serum creatinine ≥1.5 mg/dL.