Genomax Technologies

Join us for an exciting Tech Talk on Agilent Cell Analysis Portfolio for Comprehensive Cell Studies!

Discover how flow cytometry, RTCA, and Seahorse XF technologies can provide deeper insights into cell health, function, and metabolism.

📅 Date: 14 April 2026 (Tuesday)
⏰ Time: 12:00 PM – 1:00 PM
📍 Venue: IMMB Level 1, Meeting Room 1, Faculty of Medicine, UiTM Sungai Buloh

🎤 Speaker: Mr. Charlie Chin (Field Application Specialist, Genomax Technologies)

👉 Register here: https://forms.gle/tTdbfPoosRsEqUzJ7

Limited seats available – secure your spot now!

Human blood proteomics (Part 1): What and why?

Complete coverage of human proteome can be defined differently: the gene-centric approach identifies one representative protein from each gene locus using binders while protein-centric approach considers every splice variant, post-translational modification and isoform.

Bloodstream is the highway that carries various nutrients and hormones and other modulators throughout the human body for proper function. A drop of blood can essentially offer a snapshot of the overall state of an individual at a given time.

Proteins secreted or that leak into the circulation are involved in physiological processes related to blood homeostasis, transportation, defense, signaling, digestion and inhibition of other proteins, inflammation and wound healing. The presence of cellular proteins in the bloodstream may be a consequence of various complex processes, including response to damage to cells and organs.

Blood samples have high protein content which spans broad dynamic range in expression compared to cellular proteome. From a gene-centric view, the entire human proteome is approximated to be 20,000, but over 20 proteins made up ~99% of the blood proteins, with the remaining 1% containing many low-abundance proteins present at sub-pg/ml levels or discernable only under certain pathological conditions.

Changes in blood proteins concentrations can signal or drive underlying health issues. Study of the human proteome has profound significance in both basic and medical research, as well as for the biotechnological and pharmaceutical industries, particularly in the aspects of improving diagnostics, monitoring responses to therapy, predicting disease progression, and discovering novel therapeutic targets.

The relative ease of sample collection, which is also inexpensive and minimally invasive, enables longitudinal collection/testing during study or monitoring, making blood samples ideal for routine biomedical and clinical applications.

Depending on whether blood clotting is permitted or inhibited by anticoagulants during the blood draw, the eventual cell-free fluid collected upon centrifugation will be the "serum" or "plasma" sample which accommodates the proteome.

Are you looking to study human blood proteomics on plasma or serum samples? What profiling methods are you considering?

🔬 Webinar Alert: Spatial Proteomics in Action!

Join an exclusive webinar by Bruker Corporation and discover how spatial proteomics is advancing immune research in nasal polyps!

✨ What you’ll learn:
• CellScape™ Precise Spatial Proteomics (PSP) workflow
• High-resolution imaging & Weave® data analysis
• How to extract meaningful insights from complex tissue

👨‍🔬 Speakers:
• Nic West, PhD (Griffith University)
• Matthew Ingalls, PhD (Bruker Spatial Biology)
• Alice Ly, PhD (Aspect Analytics)

📅 Date: 25 March 2026
⏰ Time: 11:00 AM

👉 Secure your spot here:
https://go.brukerspatialbiology.com/CellScapeNicWestWebinar.html?mkt_tok=NzAwLUpZRi0xNzEAAAGghSvLBcFO39BzXlfAknCPc4VfRSzyDG3AQzJboqneS5TgIpFUU_AOZJMqjiy8j3os9mu_eFhFDfaYTqdO2cE