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Pacific Biosciences long read sequencing and assembly with the MARVEL algorithm generated 32.4 billion base axolotl genome assembly for an A. mexicanum strain. Another study on planarian flatworm Schmidtea mediterranea, PacBio long read sequencing and MARVEL assembly in combination with Dovetail Chicago HiRise scaffolding generated 782 million base de novo genome assembly with genomic DNA from an in**ed S. mediterranea strain.

Amphibian, Flatworm Genomes Offer Clues to Regeneration Researchers hope the genomes of the Mexican axolotl and the Schmidtea mediterranea worms will facilitate further studies on the processes behind regeneration.

Join Pacbio January 13-17 at PAG XXVI in San Diego, California and find out how Single Molecule, Real-Time (SMRT) Sequencing can help advance your research.

Here is the registration link:
https://lnkd.in/ffFYHiz

PACBIO WORKSHOP: MONDAY, JANUARY 15, 12:50-3:00 P.M. PST
Location: Town and Country Hotel, Golden West Ballroom

Speakers:

· SMRT Sequencing Highlights: Building Better Genomes and Transcriptomes
Marty Badgett, Senior Director, Product Management, PacBio

· Domestication: Through the Canines of a Dingo
Bill Ballard, Professor, Biotechnology and Biomolecular Sciences, University of New South Wales, Australia

· Long-Read Sequencing Reveals Complex Genomic Architecture in Independent Carnivorous Plant Lineages
Tanya Renner, Assistant Professor, Entomology, Pennsylvania State University

· Using Cattle Subspecies Crosses to Explore Chromosome of Origin Expression through Iso-Seq Analysis
John Williams, Professor, School of Animal and Veterinary Sciences, Davies Research Centre, University of Adelaide

PAG 2018 - Workshop, SMRT Informatics Conference, Scientific Content

Precision Medicine World Conference (PMWC), a three-day (January 22-24) Silicon Valley event focused on exploring challenges and opportunities in personalized medicine. Lori Aro, Pacbio senior director of clinical genomics, will be speaking at PMWC in the Genomic Profiling Showcase on January 24th at 11:15 am. Her presentation will update attendees on how long-read PacBio sequencing can be a good fit for clinical assay development since it provides the longest average reads, highest consensus accuracy, and most uniform coverage of any sequencing technology available today.

There’s still time to register for PMWC 2018 and they’re offering a 10% discount until January 11.

PMWC 2018: Sequencing Improvements Power Large-Scale Studies and Clinical Assays - Pacific Biosciences One of our favorite January traditions is taking part in the Precision Medicine World Conference (PMWC), a three-day Silicon Valley …

The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegans. De novo genome assembly from Pacbio single-molecule, long-read sequencing data consisting of 135 P. pacificus contigs achieved with 99% of the assembly ordered and oriented into six chromosomes. This allowed chromosomal patterns of gene density, repeat content, nucleotide diversity, linkage disequilibrium, and macrosynteny in P. pacificus characterizations with one major translocation from an autosome to the s*x chromosome in the lineage leading to C. elegans identified.

New Nematode Assembly Simplifies Search for Evolutionary Clues - Pacific Biosciences Nematodes are both simple and complex, making them one of the most attractive animal taxa to study basic biological processes, …