SPATAX

Journée maladies rares nancy/gentilly 26 février

CHRU de Nancy - Journée Maladies Rares 2025 Site Internet du Centre Hospitalier Régional Universitaire de Nancy

Transcriptomic analysis reinforces the implication of spatacsin in neuroinflammation and neurodevelopment by Toupenet et al

Transcriptomic analysis reinforces the implication of spatacsin in neuroinflammation and neurodevelopment - Scientific Reports Hereditary spastic paraplegia (HSP) encompasses a group of rare genetic diseases primarily affecting motor neurons. Among these, spastic paraplegia type 11 (SPG11) represents a complex form of HSP caused by deleterious variants in the SPG11 gene, which encodes the spatacsin protein. Previous studies...