Lung Factor

https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-023-02540-0

KIF15 missense variant is associated with the early onset of idiopathic pulmonary fibrosis - Respiratory Research Background Idiopathic pulmonary fibrosis (IPF) has an unknown aetiology and limited treatment options. A recent meta-analysis identified three novel causal variants in the TERT, SPDL1, and KIF15 genes. This observational study aimed to investigate whether the aforementioned variants cause clinical p...

BAP1 germline variants in Finnish patients with malignant mesothelioma Although asbestos exposure is the most common cause of malignant mesothelioma (MM), an aggressive cancer of the pleura or peritoneum, up to 7% of pati…

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Factor analysis identifies three separate symptom clusters in idiopathic pulmonary fibrosis Idiopathic pulmonary fibrosis (IPF) is a severe and progressive lung disease with a poor prognosis. Patients with IPF suffer from a high symptom burden, which impairs their health-related quality of life (HRQoL). Lack of research on IPF symptoms and their clustering, however, makes symptom-centred c...