Cordat Lab

Cordat Lab

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Research in the Cordat’s lab is focused on trafficking of membrane proteins in cells, with a particular emphasis on bicarbonate transporters. Any imbalance of plasma bicarbonate homeostasis alters a number of physiological processes, including homeostasis of oxalate, a component of 80 % of kidney stones, indirect regulation of water reabsorption, plasma pH homeostasis, bile duct function, spermato

03/05/2026

Welcome to Mathieu Ruyssckaert and Celebration lunch for Grace's manuscript! The ramens were delicious on this freezing day!

SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy 03/05/2026

Here is our latest publication in eLife!
https://elifesciences.org/articles/108253
Congratulations to Grace for her hard work on this project👏

SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy Distal renal tubular acidosis induced by some SLC4A1 variants is characterized by cytosolic pH alkalization, reduced ATP synthesis and defective autophagy degradative flux.

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Room 734, MSB, University Of
Edmonton, AB
T6G2H7