Stream Community Engagement

For , the Community Advisory Board in Chennai, India released a documentary on the importance of community engagement in TB research. To view the documentary, click here:

https://treattb.org/2021/04/01/chennai-stream-cab-releases-documentary-on-world-tb-day/

USAID - US Agency for International Development Vital Strategies International Union Against Tuberculosis and Lung Disease (The Union)

Chennai STREAM CAB's Journey

All participants have now completed their allocated trial treatment, paving the way for preliminary trial results to be reported in 2022. Thank you to our implementing partners and trial participants, who played a critical role in achieving this important milestone. USAID - US Agency for International Development Vital Strategies Medical Research Council

Last STREAM trial participant completes MDR-TB treatment – TREAT TB Last week, the STREAM clinical trial reached a significant milestone, when the last-recruited participant completed their allocated trial treatment regimen. A total of 588 participants at 13 sites were recruited to Stage 2 of the trial, which is expected to report results in 2022. The aim of Stage 2...

A great initiative by our colleagues in Mongolia who recently organized an online discussion on managing TB during COVID. https://www.facebook.com/CABMongol/posts/212071097081685?notif_id=1608698953285799¬if_t=page_tag&ref=notif

In Stage 1 of the , severe QT prolongation was more frequent on the short regimen. This could have been due to high dose moxifloxacin and clofazamine used in the short regimen. At the conference, Gareth Hughes from Medical Research Council reported the results of further analyses of Stage 1 data to explore whether there was a cut-off value that could allow prioritization of ECG monitoring. Results suggest that using a combination of cut-offs might permit a reduction in ECG monitoring frequency in 47% of patients on the short regimen. These results need further validation but could potentially be useful in programmatic settings with limited resources.
USAID - US Agency for International Development The Union World Conference on Lung Health

Vital Strategies Ishmael Qawiy presents data on tablet-based audiometry compared to conventional audiometry in Stage 2 of the . Head to the portal to hear his presentation! USAID - US Agency for International Development The Union World Conference on Lung Health Medical Research Council

OA-17-Safety first: side effects of old and new drugs *Please scroll down for more information* 12:30 - 12:35: Introduction 12:35 - 12:43: OA-17-605-22-Audiometry outcomes during and after drug-resistant TB treatment with a kanamycin-containing drug-regimen: drug-resistant TB patients assessed in three rural districts of Masvingo Zimbabwe The abstract....