At The Equator

Neglected Tropical diseases: Getting the dose right

Join the experts as they shine a light on these critical health challenges and work towards a healthier, more equitable future. Explore pioneering research, collaborative solutions, and innovative strategies addressing the world’s most NTDs. American Society of Tropical Medicine and Hygiene (ASTMH)

Accurate documentation of sampling and infusion times is important in population PK modeling and model-informed precision dosing. Even with small uncertainty in documented time, erroneous records impact the accuracy and precision of estimated PK parameters on the population and individuals.

Dosing Accuracy and Sampling Time Accurate documentation of sampling and infusion times in population PK modeling and model-informed precision dosing is important. Erroneous records, even wit...

PBPK models have improved model-informed drug development by assessing drug-drug interaction, dosing prediction, dose validation in pediatric patients, pregnancy dose calibration, lactational exposure and much more in the pharmaceutical field.

THE ROLE OF MODELLING PBPK models have improved model-informed drug development by assessing drug–drug interaction, dosing prediction, dose validation in pediatric patients, pregn...